vCenter REST APIs v8.0.0
The VMware vCenter Server APIs are organized around REST. For ease of use and security, REST builds on the standard web protocols HTTP and HTTPS, using the normal network ports 80 and 443, which are both open in most data centers, and uses standard HTTP response codes, authentication, and verbs.
Note: Some APIs from vCenter REST APIs -> Deployment group need to be invoked on port 5480. The API contract on port 5480 is different than the one on port 443. Please refer to this KB article for more details.